Operator Protection
Product Protection
Environmental Protection
Clean Air
General Processing Platform Isolator (GPPI)
Esco Pharma's General Processing Platform Isolator (GPPI) is a highly adaptable, unidirectional laminar airflow isolator that can be used for sterility testing or other processes that require an ISO Class 5 (Grade A) aseptic environment. The GPPI’s advanced control system allows the operator to select either positive or negative chamber pressure as well as single pass or recirculating airflow patterns.
These features, along with the ability to perform safe change procedures on the supply and return ULPA filters, make the GPPI a highly versatile isolator that can be used for potent or non-potent aseptic materials.
In addition, the Esco GPPI’s design offers over 20 standard options and configurations ensuring that Esco can provide a standard solution to fit your specific process and facility requirements. Should a standard option not fit your requirements Esco can offer customized solutions as well.
Fully welded SS316L internal chambers with rounded coved corners
Optional on-board exhaust catalytic convertor allows exhaust into the surrounding room without modifications to the facility and fitted with an interlocked external H2O2 sensor for safety
Optional on-board air compressor eliminates the requirement for a site supplied compressed air connection, which allows for the installation of a simple plug-in of electrical power
Product is designed with FDA-approved hydraulic liquid that not only allows the user to raise and lower for optimal ergonomics but also enables ease of transport through a variety of doorway and ceiling heights
Self-contained design of control system & electrics allow for simple, plug-in installation
Integrated particle monitoring connections and optional inclusion of the viable and non-viable monitoring equipment
Automated pressure hold test
Pre-Programmed system to function with multiple H2O2 system options
Standard design incorporates cGMP compliant features; with the inclusion of an optional chart recorder or printer the GPPI will meet the data handling requirements for 21 CFR Part 11 requirements
Safe change glove system allows the changing of gloves while maintaining aseptic conditions inside of the chambers
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GENERAL SPECIFICATIONS General Processing Platform Isolator (GPPI) |
GPPI-2G |
GPPI-3G |
GPPI-4G |
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Nominal Size Main Chamber (Width) |
1200 mm (55.1") |
1600 mm (62.9”) |
2000 mm (78.7”) |
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Working Chamber Dimensions (L x W x H) |
1200 x 610 x 720 mm (47.2” x 24” x 28.3”) |
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1200 x 720 x 720 mm (47.2” x 28.3” x 28.3”) |
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External Dimensions (L x W x H) |
With Adjustable Base Stand (Min) |
1920 x 920 x 2200 mm (75.5” x 36.2” x 86.6”) |
2320 x 920 x 2200 mm (91.3” x 36.2” x 86.6”) |
2720 x 920 x 2200 mm (107” x 36.2” x 86.6”) |
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With Adjustable Base Stand (Max) |
1920 x 920 x 2500 mm (75.5” x 36.2” x 98.4”) |
2320 x 920 x 2500 mm (91.3” x 36.2” x 98.4”) |
2720 x 920 x 2500 mm (107” x 36.2” x 98.4”) |
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Glove Port Height Min |
1055 mm (41.5”) |
1055 mm (41.5”) |
1055 mm (41.5”) |
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Glove Port Height Max |
1355 mm (53.3”) |
1355 mm (53.3”) |
1355 mm (53.3”) |
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Chamber Environment |
ISO Class 5 all Chambers (Grade A) |
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Filter Type -Chamber Inlet |
ULPA U15 with Integral Mesh Guard and Knife Edge Gel Seal |
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Filter Efficiency - Chamber Inlet |
99.9998% |
99.9998% |
99.9998% |
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Filter Type -Chamber Exhaust |
HEPA H14 with Integral Mesh Guard and Gasket Sealing Type |
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Filter Efficiency - Chamber Exhaust |
99.9998% |
99.9998% |
99.9998% |
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Lighting Level |
≥ 600 lux (≥ 56 foot-candles) |
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Sound Level |
68 dBA |
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Isolator Construction |
Chamber |
SS316L |
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Service Housing |
SS304L |
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Support Frame |
SS304L |
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Isolator Finish |
Chamber Internal |
≤ 0.4Ra |
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Chamber External |
≤ 0.6Ra |
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Service Housing External |
≤ 0.6Ra |
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Support Frame |
≤ 1.0Ra |
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Electrical Requirements (By Client) |
220-240V, AC, 50Hz, 1Ø |
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110-120V, AC, 60Hz, 1Ø |
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220-240V, AC, 60Hz, 1Ø |
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Compressed Air Requirement (By Client) (If no on-board compressor) |
2 Bar-g Pressure at 5Ltr/sec |
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Exhaust Duct Requirements (By Client) (Unless Integral Catalytic Convertor is Included) |
10" Duct from Isolator to Outside |
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GPPI-2G |
GPPI-3G |
GPPI-4G |
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Options |
Pass Chamber |
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Bio-Decontamination Steris |
✓ |
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Bio-Decontamination Bioquell |
✓ |
✓ |
✓ |
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Non-Viable Air Sampler |
✓ |
✓ |
✓ |
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Viable Air Sampler |
✓ |
✓ |
✓ |
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Sterility Test Pump |
✓ |
✓ |
✓ |
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Glove Tester |
✓ |
✓ |
✓ |
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Waste Bag Grommet |
✓ |
✓ |
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Sterile Continuous Liner |
✓ |
✓ |
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Bag Welder with Table |
✓ |
✓ |
✓ |
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RTPØ105, 190, 270, 350, 460 - Alpha |
✓ |
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RTPØ105, 190, 270, 350, 460 - Beta Canister |
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RTPØ105, 190, 270, 350, 460 - Beta Liner |
✓ |
✓ |
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Weigh Scale |
✓ |
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Spray Gun |
✓ |
✓ |
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Temperature and RH Monitoring |
✓ |
✓ |
✓ |
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H2O2 Monitoring |
✓ |
✓ |
✓ |
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Product Waste Entry / Exit Ports |
✓ |
✓ |
✓ |
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Liquid Water Entry / Exit Ports |
✓ |
✓ |
✓ |
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Integral Catalytic Convertor |
✓ |
✓ |
✓ |
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On-board Air Compressor |
✓ |
✓ |
✓ |
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