Glovebox is the general term used to describe a sealed chamber that allows the operator to handle hazardous materials or agents having an unknown risk level. These units provide a controlled environment for working with samples while physically separating personnel from the materials they are manipulating. Gloveboxes serve the needs of a diverse range of industries. For example, the glove box is often utilized in biotechnology, biomedical, nuclear, defense, pharmaceutical, semiconductor and chemical applications. When these enclosures are used for microbiological research or to handle pathogens, they are referred to as Class III Biological Safety Cabinets. These units provide containment for work with high-risk biological agents and must be constructed in compliance with the Biosafety in Microbiological and Biomedical Laboratories (BMBL) specifications.