Specific Manufactured Small and Large Molecules

  • Pharmaceuticals

    Antibiotics, also called antibacterial, are a type of antimicrobial drug used in the treatment and prevention of bacterial infection. They either kill or inhibit the growth of bacteria.

  • Cytotoxic drugs are agents known to be highly toxic to cells through cell reproduction and are mainly intended for the treatment of cancer. These are designed to prevent the rapid growth and division of cancer cells. Most of these medicines are carcinogenic, mutagenic and teratogenic.
  • Biosimilars are biological products licensed by FDA because they are highly similar to FDA-approved biological products, and have been shown to have no clinically meaningful differences from the reference product.
  • Antibody-drug conjugates (ADCs) are biotherapeutics that consist of monoclonal antibodies (mAbs), potent cytotoxic drugs and linkers between them. By combining the unique targeting of mAbs with the cancer-killing ability of cytotoxic drugs, ADCs allow sensitive discrimination between healthy and diseased tissue.
  • Vaccines are substances used to stimulate the antibodies production as a means of providing immunity against one or several diseases, prepared from the causative agent of a disease, its products, or a synthetic substitute, treated to act as an antigen without inducing the disease.
  • Nutraceuticals is a broad umbrella term that is used to describe any product derived from food sources with extra health benefits in addition to the basic nutritional value found in foods. They can be considered non-specific biological therapies used to promote general well-being, control symptoms and prevent malignant processes.
  • Cosmeceuticals are cosmetic products with biologically active ingredients claiming to have medical or drug-like benefits. Dermatological research suggests that the bioactive ingredients used in cosmeceuticals have benefits beyond the traditional moisturizer.
  • Phytoceuticals are any plant derived chemical that is not considered an essential or conditionally essential nutrient in the human diet but is believed to have beneficial health effects. These are products often associated with herbal medicine, some of which are known to copy a natural human related biochemical substance.
  • Food and Beverage. Food products like cheese and other dairy products; drinks like milk, wine and juices among others – require processes that enhance safety, contamination prevention and product quality.
  • Fine Chemicals/HAPIs are complex, single, pure chemical substances, produced in limited quantities in multipurpose plants by multistep batch chemical or biotechnological processes. They are described by exacting specifications, used for further processing within the chemical industry.

    Fine chemicals are produced in limited volumes (< 1000 tons/year) and at relatively high prices according to exacting specifications, mainly by traditional organic synthesis in multipurpose chemical plants. Biotechnical processes are gaining ground. The global production value is about $85 billion.

    Fine chemicals are used as starting materials for specialty chemicals, particularly pharmaceuticals, biopharmaceuticals and agrochemicals. Custom manufacturing for the life science industry plays a big role; however, a significant portion of the fine chemicals total production volume is manufactured in house by large users. The industry is fragmented and  extends from small, privately owned companies to divisions of big, diversified chemical enterprises.

    The term "fine chemicals" is used in distinction to "heavy chemicals", which are produced and  handled in large lots and are often in a crude state.

  • Agrochemicals a generic term for the various chemical products used in agriculture. In most cases, agrichemical refers to the broad range of pesticides, including insecticides, herbicides, fungicides and nematicides. It may also include synthetic fertilizers, hormones and other chemical growth agents, and concentrated stores of raw animal manure.

     Agrochemical companies are the second largest users of fine chemicals. Most products have a “pharmaceutical heritage”. As a consequence of an intensive M&A activity over the past 10–20 years, the industry now is more consolidated than the pharmaceutical industry.

    Generics play a bigger role in the agro than in the pharma industry. They represent some 70% of the global market. The incidence of the cost of the active ingredient is about 33%; i.e., much higher than in drugs. Depending on the climatic conditions affecting crop yields, consumption and prices of agrochemicals are subject to wide fluctuations from year to year, impacting also the suppliers.

  • Biofertilizers a substance which contains living microorganisms which, when applied to seeds, plant surfaces, or soil, colonizes the rhizosphere or the interior of the plant and promotes growth by increasing the supply or availability of primary nutrients to the host plant.

    Bio-fertilizers add nutrients through the natural processes of nitrogen fixation, solubilizing phosphorus, and stimulating plant growth through the synthesis of growth-promoting substances.

    Bio-fertilizers can be expected to reduce the use of chemical fertilizers and pesticides. The microorganisms in  bio-fertilizers restore the soil's natural nutrient cycle and build soil organic matter.

    Through the use of bio-fertilizers, healthy plants can be grown, while enhancing the sustainability and the health of the soil. Since they play several roles, a preferred scientific term for such beneficial bacteria is "plant-growth promoting rhizobacteria" (PGPR). Therefore, they are extremely advantageous in enriching soil fertility and fulfilling plant nutrient requirements by supplying the organic nutrients through microorganism and their by-products. Hence, bio-fertilizers do not contain any chemicals which are harmful to the living soil.

    Bio-fertilizers provide eco-friendly organic agro-input and are more cost-effective than chemical fertilizers.