Capsules are solid dosage forms in which the drug is enclosed within either a hard or soft soluble container or “shell”.
They are usually formed from gelatin; however, they also may be made from starch or other suitable substances.
|Capsule||Range of powder capacity|
The “Pin Method” of production is adapted, with the use of completely automatic machines
Utilize for the following reasons:
A. PLATE PROCESS
B. ROTARY DIE PROCESS
C. RECIPROCATING DIE PROCESS
The oldest, commercial methodSteps of Plate Process:
A continuous process of production of Soft Gelatin Capsules, invented by Scherer in 1993.
Developed in 1949Steps of Reciprocating Die Process:
— a process in which tiny particles or droplets are surrounded or coated with a continuous film of polymeric material to give more useful properties.
Importance of Microencapsulation
— Simple means of estimating content of active ingredient per capsule.